SCHEMBL4282848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4284479	0.92	ADORA2A (0.39)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4276096	0.92	GSK3B (0.42)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4271695	0.91	GSK3B (0.45)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4273168	0.90	LMNA (0.43)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4275012	0.87	GSK3B (0.41)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4269939	0.86	ADORA2A (0.40)	GSK3BCDK2ADORA2AKMT2AADORA1
	SCHEMBL4270616	0.86	GSK3B (0.44)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4282801	0.86	HPGD (0.46)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL4278828	0.86	S1PR1 (0.34)	PKMKMT2AMEN1TP53MAPT
	SCHEMBL4278398	0.85	GSK3B (0.41)	GSK3BCDK2HPGDCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.