SCHEMBL4286005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4269939	0.95	ADORA2A (0.40)	ADORA2AADORA1KLKB1KMT2ACDK2
	SCHEMBL4274973	0.94	ADORA2A (0.38)	S1PR1ADORA2AADORA1KLKB1CDK2
	SCHEMBL4284479	0.92	ADORA2A (0.39)	ADORA2AADORA1KLKB1TP53LMNA
	SCHEMBL4271209	0.92	ADORA2A (0.38)	ADORA2AADORA1KLKB1MAPTCDK2
	SCHEMBL4272753	0.92	ADORA2A (0.39)	S1PR1ADORA2AADORA1KLKB1MAPT
	SCHEMBL4271725	0.90	ADORA2A (0.37)	S1PR1ADORA2AADORA1KLKB1CDK2
	SCHEMBL4270608	0.90	KLKB1 (0.40)	ADORA2AADORA1KLKB1MEN1KMT2A
	SCHEMBL4275092	0.90	ADORA2A (0.40)	ADORA2AADORA1KLKB1KMT2ACDK2
	SCHEMBL4278827	0.90	ADORA2A (0.40)	ADORA2AADORA1KLKB1KMT2ACDK2
	SCHEMBL4273168	0.90	LMNA (0.43)	S1PR1ADORA2AKLKB1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.