⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26779895 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28987431 | 0.98 | PAOX (0.38) | — | |
| SCHEMBL18724552 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL23052855 | 0.81 | — | — | |
| SCHEMBL27238094 | 0.81 | — | — | |
| SCHEMBL25332688 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL29202547 | 0.79 | BCAT2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL18342136 | 0.79 | CYP2D6 (0.50) | — | |
| SCHEMBL18125223 | 0.79 | DPP7 (0.46) | — | |
| SCHEMBL19991828 | 0.79 | DPP7 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220433-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220439-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220435-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010111622-A2 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |