Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366245 | 0.83 | POLB (0.44) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL30612668 | 0.81 | L3MBTL1 (0.46) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL20003160 | 0.74 | KMT2A (0.45) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL4004484 | 0.74 | KMT2A (0.45) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL657937 | 0.74 | POLB (0.47) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL28192657 | 0.73 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KMT2AEPHX2MEN1 | |
| SCHEMBL15505019 | 0.73 | KDM1A (0.39) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL4399650 | 0.73 | KDM1A (0.39) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| Lithium Ion SCHEMBL29771299 | 0.72 | POLB (0.42) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL9670998 | 0.71 | POLB (0.45) | POLBL3MBTL1ALDH1A1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134666-A1 | INDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-05 | — | — | WO | disclosed |