SCHEMBL4274099

SCHEMBL4274099

COc1cc(C)c2c(OC)cc(=O)oc2c1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.88
HPGD P15428 7/20 0.88
KDM4E B2RXH2 7/20 0.88
HSD17B10 Q99714 6/20 0.88
GAA P10253 3/20 0.88
LMNA P02545 2/20 0.88
TDP1 Q9NUW8 1/20 0.88
MAOA P21397 2/20 0.54
MAPT P10636 6/20 0.54
GLA P06280 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TSHR P16473 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
CYP3A4 P08684 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TP53 P04637 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CCR4 P51679 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67224 0.93 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL27823419 0.82 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL24426667 0.79 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL5346582 0.79 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL11095245 0.79 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL31485737 0.78 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL17973508 0.75 ALDH1A1 (0.64) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL31318631 0.75 ALDH1A1 (0.55) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL9972728 0.75 PTGS1 (0.71) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL9923795 0.75 ALDH1A1 (0.64) ALDH1A1HPGDKDM4EHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106038728-B Effective component of clematis root and preparation method and application thereof 成都大学 2020-04-28 CN claimed
CN-107810918-A A kind of cultural method of No. two chickens in Plain 广西平南县平原农牧有限公司 2018-03-20 CN claimed
CN-102816933-A Treatment process method of chrome slag GONGXIN HUAXIN TECHNOLOGY INDUSTRY CO LTD 2012-12-12 CN claimed
CN-102276565-A Method for extracting and separating siderin 2011-12-14 CN claimed
US-20260102484-A1 ADJUVANTS FOR ENHANCING THE IMMUNE RESPONSE LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2026-04-16 US disclosed
EP-4599856-A1 SCAR REDUCING WOUND CLOSURE MATERIALS Lankenau Institute for Medical Research (US) 2025-08-13 EP disclosed
EP-4587049-A1 ADJUVANTS FOR ENHANCING THE IMMUNE RESPONSE Lankenau Institute for Medical Research (US) 2025-07-23 EP disclosed
WO-2024059321-A1 ADJUVANTS FOR ENHANCING THE IMMUNE RESPONSE LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2024-03-21 WO disclosed
US-20220176011-A1 SCAR REDUCING WOUND CLOSURE MATERIALS LANKENAU INSTITUTE FOR MEDICAL RESEARCH 2022-06-09 US disclosed
CN-114173801-A Materials and methods for multidirectional biological transport 詹森生物科技公司 2022-03-11 CN disclosed
EP-3927383-A1 SCAR REDUCING WOUND CLOSURE MATERIALS Lankenau Institute for Medical Research (US) 2021-12-29 EP disclosed
CN-108634364-B Couch grass extract, preparation method thereof and application thereof in cigarettes 河南中烟工业有限责任公司 2021-05-18 CN disclosed
US-6953575-B2 Methods of treating central nervous system disorders using viral vectors AVIGEN, INC. (US) 2005-10-11 US disclosed
US-6309634-B1 DELIVERING VIRAL VECTORS TO THE CNS ARE PROVIDED. AVIGEN, INC. 2001-10-30 US disclosed
WO-1998041226-A9 PHARMACEUTICAL COMBINED PREPARATIONS CONTAINING ERYTHROPOIETIN AND IRON PREPARATIONS ROCHE DIAGNOSTICS GMBH (DE) 1999-11-25 WO disclosed
EP-0851762-A1 PHARMACEUTICAL COMBINATION PREPARATIONS CONTAINING ERYTHROPOIETIN AND IRON PREPARATIONS Roche Diagnostics GmbH (DE) 1998-07-08 EP disclosed
WO-1997009996-A1 PHARMACEUTICAL COMBINATION PREPARATIONS CONTAINING ERYTHROPOIETIN AND IRON PREPARATIONS BOEHRINGER MANNHEIM GMBH (DE) 1997-03-20 WO disclosed
EP-0559691-A1 TREATMENT OF EXERCISE-INDUCED PULMONARY HEMORRHAGE IN ANIMALS. MILLS JOHN A (CA) 1993-09-15 EP disclosed
WO-1988003808-A1 METHOD FOR TREATING IRON OVERLOAD KIRIN-AMGEN, INC. (US) 1988-06-02 WO disclosed
EP-0269394-A2 Method for treating iron overload Kirin-Amgen, Inc. (US) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102484-A1 ADJUVANTS FOR ENHANCING THE IMMUNE RESPONSE HIF1A, HIF1AN, EGLN3 ALDH1A1 2541/4885HPGD 305/4885KDM4E 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.