SCHEMBL67224

SCHEMBL67224

COc1cc(OC)c2c(C)cc(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
KDM4E B2RXH2 7/20 1.00
HPGD P15428 7/20 1.00
HSD17B10 Q99714 6/20 1.00
GAA P10253 3/20 1.00
LMNA P02545 2/20 1.00
TDP1 Q9NUW8 1/20 1.00
MAOA P21397 3/20 0.61
MAPT P10636 4/20 0.60
GLA P06280 3/20 0.60
TSHR P16473 1/20 0.60
CASP1 P29466 1/20 0.60
CASP7 P55210 1/20 0.60
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP3A4 P08684 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ABCB1 P08183 2/20 0.52
CCR4 P51679 1/20 0.52
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274099 0.93 ALDH1A1 (0.88) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL24426667 0.82 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL5346582 0.82 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL11095245 0.82 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL27823419 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL17973508 0.78 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL9923795 0.78 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL15842656 0.78 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL30140588 0.77 ALDH1A1 (0.82) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL8833383 0.77 XDH (0.70) ALDH1A1KDM4EHPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US claimed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US disclosed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US disclosed
US-8129087-B2 Block copolymer and substrate processing method CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
CN-101497632-B Method for synthesizing coumarin-3-phosphonate derivative UNIV SOOCHOW 2012-01-25 CN disclosed
CN-101256358-B Photosensitive compound, polyhydroxystyrene and novolac resin CANON KK 2011-06-22 CN disclosed
US-20090311637-A1 BLOCK COPOLYMER AND SUBSTRATE PROCESSING METHOD CANON KABUSHIKI KAISHA (JP) 2009-12-17 US disclosed
US-7615332-B2 Photosensitive compound, photosensitive composition, resist pattern forming method, and device production process CANON KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-20090233232-A1 PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE COMPOSITION, RESIST PATTERN FORMING METHOD, AND DEVICE PRODUCTION PROCESS CANON KABUSHIKI KAISHA (JP) 2009-09-17 US disclosed
CN-101497632-A Method for synthesizing coumarin-3-phosphonate derivative UNIV SOOCHOW (CN) 2009-08-05 CN disclosed
CN-101256358-A Photosensitive compound, photosensitive composition, resist pattern forming method, and device production process CANON KK (JP) 2008-09-03 CN disclosed
EP-1956430-A1 Photosensitive compound, photosensitive composition, resist pattern forming method, and device production process Canon Kabushiki Kaisha (JP) 2008-08-13 EP disclosed
US-20080187864-A1 PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE COMPOSITION, RESIST PATTERN FORMING METHOD, AND DEVICE PRODUCTION PROCESS CANON KABUSHIKI KAISHA (JP) 2008-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233232-A1 PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE COMPOSITION, RESIST PATTERN FORMING METHOD, AND DEVICE PRODUCTION PROCESS FRG1, PAH, RER1 ALDH1A1 1256/4885KDM4E 2439/4885HPGD 2184/4885
US-20080187864-A1 PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE COMPOSITION, RESIST PATTERN FORMING METHOD, AND DEVICE PRODUCTION PROCESS FRG1, PAH, RER1 ALDH1A1 1256/4885KDM4E 2439/4885HPGD 2184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.