SCHEMBL4274825

SCHEMBL4274825

CC1OCC(C(=O)OCC(c2ccc(C(C)(C)C)c(O)c2C(C)(C)C)(C2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)(C(=O)OCC(c2ccc(C(C)(C)C)c(O)c2C(C)(C)C)(C2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)CO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274838 0.70 MEN1 (0.32)
SCHEMBL17877405 0.63 GAA (0.33) EZH2
SCHEMBL8026597 0.62 GAA (0.43)
SCHEMBL17877392 0.62 GAA (0.34) EZH2
SCHEMBL17877402 0.59
SCHEMBL10906475 0.56 CA2 (0.56)
SCHEMBL11166915 0.56 TSHR (0.44) EZH2
SCHEMBL11155371 0.55 GAA (0.37)
SCHEMBL11168645 0.55 EZH2 (0.44) EZH2
SCHEMBL11489217 0.54 HMGCR (0.43) EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090075048-A1 Cellulose-mixed ester film and method for producing same FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed