SCHEMBL4274838

SCHEMBL4274838

CC1OCC(C(=O)O)(C(=O)OC(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(C2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)CO1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 2/20 0.32
BLM P54132 2/20 0.32
ATM Q13315 2/20 0.32
HIF1A Q16665 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
USP2 O75604 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
GMNN O75496 1/20 0.31
GABBR2 O75899 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075835 0.70 ALDH1A1 (0.39) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL4274825 0.70 EZH2 (0.32)
SCHEMBL7795980 0.67 ALDH1A1 (0.37) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL11461381 0.67 ALDH1A1 (0.35) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL5075832 0.67 ALDH1A1 (0.41) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL20428970 0.67 ALDH1A1 (0.41) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL4274799 0.66 KMT2A (0.36) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL9813579 0.65 KMT2A (0.48) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL11500094 0.64 KMT2A (0.39) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL13599660 0.64 ALDH1A1 (0.39) MEN1KMT2AALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090075048-A1 Cellulose-mixed ester film and method for producing same FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed