SCHEMBL4275778

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4275333	0.92	S1PR1 (0.38)	MAPTKDM4EMEN1NPC1RAB9A
	SCHEMBL4284539	0.92	DHODH (0.40)	MAPTTHRBKDM4EMEN1NPC1
	SCHEMBL4270538	0.92	S1PR1 (0.36)	LCLAT1FFAR1PPARGPPARAS1PR1
	SCHEMBL13701432	0.91	MAPT (0.39)	MAPTTHRBKDM4EMEN1NPC1
	SCHEMBL4277067	0.91	FFAR1 (0.34)	LCLAT1MAPTFFAR1TP53LMNA
	SCHEMBL4276856	0.91	PDE4B (0.35)	MAPTTHRBKDM4EMEN1NPC1
	SCHEMBL4273664	0.90	PDE4A (0.38)	MAPTTHRBKDM4EMEN1NPC1
	SCHEMBL4269872	0.90	SMN1; SMN2 (0.42)	MAPTKDM4EMEN1NPC1HTT
	SCHEMBL4286018	0.88	PPARG (0.37)	LCLAT1MAPTTHRBKDM4EMEN1
	SCHEMBL4278392	0.88	FPR2 (0.41)	PDE4APDE4BPDE4CPDE4DLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.