SCHEMBL4286018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4270647	0.96	PPARG (0.39)	PPARGPPARAS1PR1S1PR5S1PR3
	SCHEMBL4276646	0.93	PPARG (0.38)	PPARGPPARAS1PR1S1PR5S1PR3
	SCHEMBL13701432	0.91	MAPT (0.39)	KDM4EKMT2AALDH1A1HTTMAPT
	SCHEMBL13701625	0.91	PPARG (0.38)	PPARGPPARAS1PR1S1PR5S1PR3
	SCHEMBL4273664	0.90	PDE4A (0.38)	PPARGPPARAS1PR1KDM4EKMT2A
	SCHEMBL4269872	0.90	SMN1; SMN2 (0.42)	S1PR1S1PR3KDM4EKMT2AALDH1A1
	SCHEMBL4275778	0.88	LCLAT1 (0.34)	PPARGPPARAS1PR1S1PR5S1PR3
	SCHEMBL4278392	0.88	FPR2 (0.41)	NPSR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL13701439	0.88	MAPT (0.35)	PPARGPPARAKDM4EKMT2AALDH1A1
	SCHEMBL4284539	0.87	DHODH (0.40)	PPARGPPARAS1PR1S1PR5S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.