⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813452 | 0.83 | NAAA (0.44) | — | |
| SCHEMBL7036037 | 0.81 | NAAA (0.47) | — | |
| SCHEMBL9741621 | 0.79 | NAAA (0.50) | — | |
| SCHEMBL29263650 | 0.79 | NAAA (0.50) | — | |
| SCHEMBL1299755 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL239378 | 0.75 | — | — | |
| SCHEMBL467539 | 0.74 | — | — | |
| SCHEMBL10452274 | 0.73 | NAAA (0.39) | — | |
| SCHEMBL12494840 | 0.72 | CA2 (0.39) | — | |
| SCHEMBL28036517 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528820-A | Apricoxiyet Synthesis method of tam | 浙江国邦药业有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-115321695-B | Coagulation-aiding decoloration softener and preparation method and application thereof | 浙江碧源环保科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-115321695-A | Coagulation-aiding decoloration softening agent and preparation method and application thereof | 浙江碧源环保科技有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-101575315-B | New naphthalimide derivative, preparation method and application thereof | UNIV BEIJING | 2011-05-25 | — | — | CN | claimed |
| CN-101575315-A | New naphthalimide derivative, preparation method and application thereof | UNIV BEIJING (CN) | 2009-11-11 | — | — | CN | claimed |
| US-12630566-B2 | KRas G12D inhibitors | Mirati Therapeutics, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| CN-119528820-B | Apricoxiyet Synthesis method of tam | 浙江国邦药业有限公司 | 2025-10-10 | — | — | CN | disclosed |
| EP-4536356-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | Xenon Pharmaceuticals Inc. (CA) | 2025-04-16 | — | — | EP | disclosed |
| CN-119528820-A | Apricoxiyet Synthesis method of tam | 浙江国邦药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119528820-A | Apricoxiyet Synthesis method of tam | 浙江国邦药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20240309020-A1 | KRAS G12D INHIBITORS | ARRAY BIOPHARMA INC. | 2024-09-19 | — | — | US | disclosed |
| CN-115321695-B | Coagulation-aiding decoloration softener and preparation method and application thereof | 浙江碧源环保科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-4293699-A | CONTAINING A BENZIMIDAZOLE OR 3-/5,6,7,8-TETRAHYDROIMIDAZO(1,5A)PYRIDINE, ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4228291-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |
| US-4221802-A | Pharmacologically active guanidine compounds for inhibiting H-2 histamine receptors | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-09 | — | — | US | disclosed |
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |