Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49494 | 0.91 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL27957204 | 0.88 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL9345851 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3CES2 | |
| SCHEMBL28289364 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3CES2 | |
| SCHEMBL709944 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3CES2 | |
| SCHEMBL28443818 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3CES2 | |
| SCHEMBL27700114 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3CES2 | |
| Hydrochloric Acid SCHEMBL28156324 | 0.88 | ESR1 (0.40) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL11904130 | 0.85 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CES2 | |
| Toluene SCHEMBL27693706 | 0.83 | ACHE (0.58) | ESR1ESR2NR1H2NR1H3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |