SCHEMBL49494

SCHEMBL49494

O[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CA4 P22748 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CA1 P00915 1/20 0.39
GLA P06280 1/20 0.39
CA9 Q16790 1/20 0.39
BBOX1 O75936 2/20 0.37
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
APP P05067 1/20 0.37
NR1H2 P55055 2/20 0.37
NR1H3 Q13133 2/20 0.37
ALDH1A1 P00352 3/20 0.35
IDO1 P14902 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28443818 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
Hydrochloric Acid SCHEMBL28156324 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL709944 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL9345851 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL27700114 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL28289364 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL11904130 0.94 ESR1 (0.39) ESR1ESR2CA4CA14CA12
Formaldehyde SCHEMBL8724973 0.91 ESR1 (0.37) ESR1ESR2CA4CA14CA12
SCHEMBL4276199 0.91 ESR1 (0.48) ESR1ESR2CA4CA14CA12
SCHEMBL4619383 0.91 ESR1 (0.37) ESR1ESR2CA4CA14CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8374 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080359-A Silicon modified waterborne polyurethane and preparation method thereof 2026-05-26 CN claimed
CN-122080537-A Rubber compound for carbon-free insulating cooling rubber tube and preparation method thereof 2026-05-26 CN claimed
CN-119331177-B Modified polyurethane dispersoid and preparation method thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122011657-A Modified silicon rubber composite material, preparation method thereof, sealing product and oil immersed capacitor 广东电网有限责任公司广州供电局 2026-05-12 CN claimed
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
EP-4680687-A1 SOFT POLYSILOXANE CORE-SHELL ABRASIVES FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2026-01-21 EP claimed
US-20250388723-A1 SILYL ETHER-CONTAINING POLYMERS AND USES THEREOF ENTEGRIS INC (US) 2025-12-25 US claimed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP claimed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP claimed
EP-4634324-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2025-10-22 EP claimed
US-4324873-A Organosilicon-organometal compositions as epoxy curing catalysts TOKYO SHIBAURA DENKI KABUSHIKI KAISAHA (JP) 1982-04-13 US claimed
US-4320044-A IRON SESQUIOXIDE OR FERROFERRIC OXIDE MIXTURES FOR FIREPROOFING TORAY SILICONE COMPANY, LTD. (JP) 1982-03-16 US claimed
US-4289891-A HYDROLYSIS OF APPROPRIATE CHLOROSILANES, INEXPENSIVE GENERAL ELECTRIC COMPANY (US) 1981-09-15 US claimed
EP-0022049-A1 Process for preparing polymers that contain imide groups and that are modified with silicon, and the polymers obtained by this process RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-01-07 EP claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4228270-A Polyborodiphenylsiloxanes ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-10-14 US claimed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US claimed
US-4035332-A Water-soluble silicone-modified resin compositions SHIN-ETSU CHEMICAL CO., (JA) 1977-07-12 US claimed
US-4006226-A Anticonvulsant diphenylsilanes DOW CORNING CORPORATION (US) 1977-02-01 US claimed
US-3950308-A POLYAMIDES, POLYIMIDES, POLYAMIDE-IMIDES CIBA-GEIGY CORPORATION (US) 1976-04-13 US claimed