Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592427 | 0.84 | GPR35 (0.41) | GPR35CYP2A6SRC | |
| SCHEMBL13592428 | 0.81 | GPR35 (0.39) | GPR35 | |
| SCHEMBL12892231 | 0.80 | GPR35 (0.42) | GPR35 | |
| SCHEMBL12892233 | 0.80 | GPR35 (0.42) | GPR35 | |
| SCHEMBL1252247 | 0.79 | KDM4E (0.39) | GPR35KDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL1252615 | 0.79 | KDM4E (0.39) | GPR35KDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL994046 | 0.76 | GPR35 (0.41) | GPR35KDM4EALDH1A1LMNACYP2A6 | |
| SCHEMBL12430808 | 0.76 | MAPT (0.43) | GPR35KDM4ETP53CYP3A4HSD17B10 | |
| SCHEMBL4276519 | 0.76 | GPR35 (0.37) | GPR35KDM4EALDH1A1LMNARIPK2 | |
| SCHEMBL12892236 | 0.75 | KCNH2 (0.37) | GPR35ALDH1A1TP53CYP3A4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181509-A1 | POLYMER SEMICONDUCTORS WITH HIGH MOBILITY | XEROX CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |