SCHEMBL4276519

SCHEMBL4276519

CCCCCCCCCCCCc1c(-c2sccc2C)sc2cc3cc(-c4sccc4C)sc3c(CCCCCCCCCCCC)c12

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.37
RAD52 P43351 1/20 0.33
RIPK2 O43353 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994046 0.77 GPR35 (0.41) GPR35RAD52RIPK2KDM4EALDH1A1
SCHEMBL4276515 0.76 GPR35 (0.42) GPR35RIPK2KDM4EALDH1A1LMNA
SCHEMBL13592427 0.67 GPR35 (0.41) GPR35
SCHEMBL336507 0.66 GPR35 (0.40) GPR35
SCHEMBL994650 0.66 GPR35 (0.40) GPR35
SCHEMBL14217344 0.65 GPR35 (0.34) GPR35
SCHEMBL1828423 0.65 TYR (0.37) GPR35
SCHEMBL1829801 0.65 TYR (0.37) GPR35
SCHEMBL13592428 0.65 GPR35 (0.39) GPR35
SCHEMBL12194784 0.64 GPR35 (0.34) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090181509-A1 POLYMER SEMICONDUCTORS WITH HIGH MOBILITY XEROX CORPORATION (US) 2009-07-16 US disclosed