SCHEMBL4276702

SCHEMBL4276702

CCSCC/C=C(\C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
CD81 P60033 2/20 0.36
PPARG P37231 1/20 0.32
PTGS1 P23219 1/20 0.32
EP300 Q09472 1/20 0.31
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2523050 1.00 TSHR (0.42) TSHRCD81PPARGPTGS1EP300
SCHEMBL9407669 0.89 CD81 (0.39) TSHRCD81PPARGPTGS1EP300
SCHEMBL22528431 0.87 CD81 (0.38) TSHRCD81PPARGPTGS1BACE1
SCHEMBL9983159 0.82 TDP1 (0.40) TSHRCD81PPARGPTGS1BACE1
SCHEMBL9571096 0.82 CD81 (0.35) CD81PPARGBACE1
SCHEMBL28569115 0.80 CD81 (0.37) CD81PPARGPTGS1
SCHEMBL20837813 0.80 CES2 (0.50) PTGS1EP300
SCHEMBL7649872 0.80 CES2 (0.50) PTGS1EP300
SCHEMBL20837814 0.80 CES2 (0.50) PTGS1EP300
SCHEMBL1704918 0.78 TDP1 (0.42) CD81PPARGPTGS1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
EP-1781098-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2007-05-09 EP disclosed
WO-2006015317-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2006-02-09 WO disclosed
EP-0933399-B1 Aminosilicone oil emulsions crosslinked by Michael addition-type reactions WACKER CHEMIE GMBH (DE) 2000-09-13 EP disclosed
EP-0972811-A1 Radiation curable copolymer compositions Wacker-Chemie GmbH (DE) 2000-01-19 EP disclosed
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
EP-0933399-A1 Aminosilicone oil emulsions crosslinked by Michael addition-type reactions Wacker-Chemie GmbH (DE) 1999-08-04 EP disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
US-5587279-A HIGH CONCENTRATION OF SILVER CHLORIDE GRAINS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-24 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 TSHR 4664/4885CD81 467/4885PPARG 1792/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 TSHR 4664/4885CD81 467/4885PPARG 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.