Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.67 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL598805 | 1.00 | SLC7A5 (0.67) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Tyrosine SCHEMBL5605357 | 1.00 | SLC7A5 (0.67) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Tyrosine SCHEMBL27434350 | 0.93 | SLC7A5 (0.77) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL27703156 | 0.93 | SLC7A5 (0.77) | SLC7A5ALPIPKMPTGS1XIAP | |
| Oleic Acid SCHEMBL28343224 | 0.93 | SLC7A5 (0.57) | SLC7A5PTGS1PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL466917 | 0.93 | SLC7A5 (0.57) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Decanoic Acid SCHEMBL17667545 | 0.89 | ALPI (0.65) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL598090 | 0.89 | ALPI (0.65) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dodecanoate SCHEMBL599337 | 0.89 | ALPI (0.65) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL598091 | 0.89 | ALPI (0.65) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133163-B | Isolated chimeric proteins of modified 2, 4-dioxotetrahydropteridine synthases | GOLDGENE LLC | 2013-04-24 | — | — | CN | claimed |
| EP-1776456-B1 | ISOLATED CHIMERIC PROTEINS OF MODIFIED LUMAZINE SYNTHASE | GOLDGENE LLC (AR) | 2013-02-20 | — | — | EP | claimed |
| US-20090087435-A1 | Isolated Chimeric Proteins Of Modified Lumazine Synthase | GOLDGENE LLC (AR) | 2009-04-02 | — | — | US | claimed |
| EP-1776456-A4 | ISOLATED CHIMERIC PROTEINS OF MODIFIED LUMAZINE SYNTHASE | GOLDGENE LLC (AR) | 2008-06-18 | — | — | EP | claimed |
| CN-101133163-A | Isolated chimeric proteins of modified 2, 4-dioxotetrahydropteridine synthases | GOLDGENE LLC (AR) | 2008-02-27 | — | — | CN | claimed |
| EP-1776456-A2 | ISOLATED CHIMERIC PROTEINS OF MODIFIED LUMAZINE SYNTHASE | Goldgene LLC (AR) | 2007-04-25 | — | — | EP | claimed |
| WO-2005121330-A2 | ISOLATED CHIMERIC PROTEINS OF MODIFIED LUMAZINE SYNTHASE | GOLDGENE LLC (AR) | 2005-12-22 | — | — | WO | claimed |
| US-20210187096-A1 | UNIVERSAL VACCINE FOR VIRAL DISEASES | BIOGENESIS BAGO URUGUAY S A (UY) | 2021-06-24 | — | — | US | disclosed |
| US-10940196-B2 | Universal vaccine for viral diseases | BIOGENESIS BAGÓ HONG-KONG LIMITED (CN) | 2021-03-09 | — | — | US | disclosed |
| US-20190142926-A1 | UNIVERSAL VACCINE FOR VIRAL DISEASES | BIOGÉNESIS BAGÓ URUGUAY S.A. (UY) | 2019-05-16 | — | — | US | disclosed |
| EP-3443097-A1 | UNIVERSAL VACCINE FOR VIRAL DISEASES | Biogénesis Bagó Uruguay S.A. (UY) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178945-A1 | UNIVERSAL VACCINE FOR VIRAL DISEASES | BIOGÉNESIS BAGÓ URUGUAY S.A. (UY) | 2017-10-19 | — | — | WO | disclosed |
| CN-101133163-B | Isolated chimeric proteins of modified 2, 4-dioxotetrahydropteridine synthases | GOLDGENE LLC | 2013-04-24 | — | — | CN | disclosed |
| CN-101133163-A | Isolated chimeric proteins of modified 2, 4-dioxotetrahydropteridine synthases | GOLDGENE LLC (AR) | 2008-02-27 | — | — | CN | disclosed |