Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.57 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL4276901 | 0.93 | SLC7A5 (0.67) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Tyrosine SCHEMBL598805 | 0.93 | SLC7A5 (0.67) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Tyrosine SCHEMBL5605357 | 0.93 | SLC7A5 (0.67) | SLC7A5S1PR2S1PR1S1PR3ALPI | |
| Tyrosine SCHEMBL1537211 | 0.86 | SLC7A5 (0.77) | SLC7A5FOLH1ALPIPKMPTGS1 | |
| Tyrosine SCHEMBL302978 | 0.86 | SLC7A5 (0.77) | SLC7A5FOLH1ALPIPKMPTGS1 | |
| Tyrosine SCHEMBL18249967 | 0.86 | SLC7A5 (0.77) | SLC7A5FOLH1ALPIPKMPTGS1 | |
| Tyrosine SCHEMBL302977 | 0.86 | SLC7A5 (0.77) | SLC7A5FOLH1ALPIPKMPTGS1 | |
| Tyrosine SCHEMBL27703156 | 0.86 | SLC7A5 (0.77) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL27434350 | 0.86 | SLC7A5 (0.77) | SLC7A5ALPIPKMPTGS1XIAP | |
| Oleic Acid SCHEMBL28343224 | 0.86 | SLC7A5 (0.57) | SLC7A5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403536-B1 | ORAL DELIVERY OF HYDROPHILIC DRUGS TO THE BRAIN | UNIV LONDON (GB) | 2021-11-17 | — | — | EP | disclosed |
| US-8920819-B2 | Delivery of hydrophilic drugs | UNIVERSITY COLLEGE LONDON (GB) | 2014-12-30 | — | — | US | disclosed |
| US-20130034590-A1 | Delivery of Hydrophilic Drugs | UNIVERSITY COLLEGE LONDON (GB) | 2013-02-07 | — | — | US | disclosed |
| US-8278277-B2 | Delivery of hydrophilic drugs | UNIVERSITY COLLEGE LONDON (GB) | 2012-10-02 | — | — | US | disclosed |
| EP-2403536-A1 | ORAL DELIVERY OF HYDROPHILIC DRUGS TO THE BRAIN | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100479-A1 | ORAL DELIVERY OF HYDROPHILIC DRUGS TO THE BRAIN | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-10 | — | — | WO | disclosed |
| US-20100222281-A1 | DELIVERY OF HYDROPHILIC DRUGS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130034590-A1 | Delivery of Hydrophilic Drugs | AQP4, LIPA, ABCB11 | SLC7A5 125/4885IL1RN 3858/4885ERAP2 1824/4885 |
| US-20100222281-A1 | DELIVERY OF HYDROPHILIC DRUGS | AQP4, LIPA, ABCB11 | SLC7A5 125/4885IL1RN 3858/4885ERAP2 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.