Tyrosine

Tyrosine

SCHEMBL598805

CCCCCCCC(=O)O.NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.67
S1PR2 O95136 1/20 0.49
S1PR1 P21453 1/20 0.49
S1PR3 Q99500 1/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
LTA4H P09960 1/20 0.48
HSD17B3 P37058 5/20 0.48
PPARG P37231 6/20 0.47
PPARD Q03181 6/20 0.47
PPARA Q07869 6/20 0.47
GPR84 Q9NQS5 5/20 0.47
HDAC11 Q96DB2 5/20 0.47
TSHR P16473 4/20 0.47
ALDH1A1 P00352 2/20 0.47
TLR2 O60603 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
FABP4 P15090 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL5605357 1.00 SLC7A5 (0.67) SLC7A5S1PR2S1PR1S1PR3ALPI
Stearic Acid SCHEMBL4276901 1.00 SLC7A5 (0.67) SLC7A5S1PR2S1PR1S1PR3ALPI
Tyrosine SCHEMBL27434350 0.93 SLC7A5 (0.77) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL27703156 0.93 SLC7A5 (0.77) SLC7A5ALPIPKMPTGS1XIAP
Oleic Acid SCHEMBL28343224 0.93 SLC7A5 (0.57) SLC7A5PTGS1PPARGPPARDPPARA
Palmitic Acid SCHEMBL466917 0.93 SLC7A5 (0.57) SLC7A5S1PR2S1PR1S1PR3ALPI
Decanoic Acid SCHEMBL17667545 0.89 ALPI (0.65) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL598090 0.89 ALPI (0.65) SLC7A5ALPIPKMPTGS1XIAP
Dodecanoate SCHEMBL599337 0.89 ALPI (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL598091 0.89 ALPI (0.65) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115192706-B Preparation method of novel gold nanoparticle and application of novel gold nanoparticle in tumor treatment 中国医学科学院肿瘤医院 2023-05-26 CN disclosed
CN-115192706-A Preparation method of novel gold nanoparticles and application of novel gold nanoparticles in tumor treatment 中国医学科学院肿瘤医院 2022-10-18 CN disclosed
EP-1948199-B1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LAB INC (US) 2015-08-12 EP disclosed
EP-1960415-B1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LAB INC (US) 2015-03-04 EP disclosed
US-8293253-B2 Compositions for controlled delivery of pharmaceutically active compounds IDEXX LABORATORIES, INC. (US) 2012-10-23 US disclosed
US-8114440-B2 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. (US) 2012-02-14 US disclosed
US-8017159-B2 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LABORATORIES, INC. (US) 2011-09-13 US disclosed
US-20100240741-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LABORATORIES, INC. (US) 2010-09-23 US disclosed
US-20100204303-A1 Pharmaceutical Compositions for Administering Oligonucleotides IDEXX LABORATORIES, INC. (US) 2010-08-12 US disclosed
US-7754679-B2 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES, INC. (US) 2010-07-13 US disclosed
EP-1960415-A2 PHOSPHOLIPID GEL COMPOSITIONS FOR DELIVERY OF APTAMERS AND METHODS OF TREATING CONDITIONS USING SAME IDEXX Laboratories Inc (US) 2008-08-27 EP disclosed
EP-1948199-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX Laboratories Inc (US) 2008-07-30 EP disclosed
EP-1804771-A2 COMPOSITIONS FOR CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS IDEXX LABORATORIES, INC. (US) 2007-07-11 EP disclosed
WO-2007058800-A2 PHOSPHOLIPID GEL COMPOSITIONS FOR DELIVERY OF APTAMERS AND METHODS OF TREATING CONDITIONS USING SAME IDEXX LABORATORIES INC. (US) 2007-05-24 WO disclosed
WO-2007058801-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LABORATORIES INC. (US) 2007-05-24 WO disclosed
US-20070110775-A1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LABORATORIES INC. 2007-05-17 US disclosed
US-20070110827-A1 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. 2007-05-17 US disclosed
US-20070111969-A1 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. 2007-05-17 US disclosed
WO-2006050002-A2 COMPOSITIONS FOR CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS IDEXX LABORATORIES, INC. (US) 2006-05-11 WO disclosed
US-20060093632-A1 Compositions for controlled delivery of pharmaceutically active compounds IDEXX LABORATORIES, INC. 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060093632-A1 Compositions for controlled delivery of pharmaceutically active compounds LIPA, CEL, LPXN SLC7A5 1567/4885S1PR2 1725/4885S1PR1 1569/4885
US-20100240741-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS PHOSPHO1, SGMS1, PCYT1A SLC7A5 228/4885S1PR2 29/4885S1PR1 38/4885
US-20070111969-A1 Pharmaceutical compositions for the administration of aptamers PHOSPHO1, SGMS1, PCYT1A SLC7A5 228/4885S1PR2 29/4885S1PR1 38/4885
US-20100204303-A1 Pharmaceutical Compositions for Administering Oligonucleotides SLCO2A1, SLCO1A2, SLCO2B1 SLC7A5 16/4885S1PR2 754/4885S1PR1 977/4885
US-20070110827-A1 Pharmaceutical compositions for the administration of aptamers PHOSPHO1, SGMS1, PCYT1A SLC7A5 228/4885S1PR2 29/4885S1PR1 38/4885
US-20070110775-A1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same ANXA6, ANXA2, PLTP SLC7A5 2133/4885S1PR2 96/4885S1PR1 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.