SCHEMBL4277449

SCHEMBL4277449

C=CCOC(C)OC(=O)CCC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 2/20 0.34
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
FAAH O00519 2/20 0.31
MGLL Q99685 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4277441 0.93 TDP1 (0.39) TDP1TSHRFAAHMGLLLMNA
SCHEMBL5451680 0.82 MAPT (0.39) TDP1ABCC4MAPTSLC6A2BLM
SCHEMBL10482085 0.80 TDP1 (0.36) TDP1TSHRMEN1KMT2A
SCHEMBL24454652 0.79 EGLN1 (0.48) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL4276265 0.79 EGLN1 (0.38) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL2306723 0.78 LMNA (0.42) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL10482082 0.77 TDP1 (0.37) TDP1TSHR
SCHEMBL633708 0.77 TSHR (0.40) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL141387 0.76 TSHR (0.41) TDP1TSHRMAPTBLMLMNA
SCHEMBL20511535 0.76 TDP1 (0.39) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US claimed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP claimed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP claimed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO claimed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP claimed
EP-1966253-B1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2015-08-12 EP disclosed
US-20130184400-A1 Coating of substrates with curable fluorinated copolymers DAIKIN INDUSTRIES, LTD. (CN) 2013-07-18 US disclosed
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US disclosed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP disclosed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP disclosed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO disclosed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP disclosed