SCHEMBL4277441

SCHEMBL4277441

C=CCOC(C)OC(=O)CCC(=O)OC(C)OCC=C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 3/20 0.38
FAAH O00519 4/20 0.34
MGLL Q99685 3/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 1/20 0.32
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4277449 0.93 EGLN1 (0.36) TDP1TSHRFAAHMGLLLMNA
SCHEMBL10482082 0.83 TDP1 (0.37) TDP1TSHRALDH1A1
SCHEMBL10482085 0.82 TDP1 (0.36) TDP1TSHRALDH1A1
SCHEMBL141387 0.82 TSHR (0.41) TDP1TSHRLMNAALDH1A1
SCHEMBL1886950 0.80 TSHR (0.44) TDP1TSHRALDH1A1
SCHEMBL1173040 0.80 TSHR (0.38) TDP1TSHRLMNA
SCHEMBL7643553 0.80 HCAR2 (0.41) TDP1TSHR
SCHEMBL11108421 0.80 TDP1 (0.35) TDP1TSHR
SCHEMBL4449417 0.80 HCAR2 (0.41) TDP1TSHR
SCHEMBL10824304 0.79 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US claimed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP claimed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP claimed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO claimed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP claimed
EP-1966253-B1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2015-08-12 EP disclosed
US-20130184400-A1 Coating of substrates with curable fluorinated copolymers DAIKIN INDUSTRIES, LTD. (CN) 2013-07-18 US disclosed
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US disclosed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP disclosed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP disclosed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO disclosed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP disclosed