SCHEMBL4277625

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4270628	0.90	S1PR1 (0.43)	LMNAMAPTMAPK1NPC1SMN1; SMN2
	SCHEMBL4276071	0.89	MGAM (0.37)	MAPTSMN1; SMN2CYP19A1PPARGPPARA
	SCHEMBL4271880	0.87	TSHR (0.41)	LMNAMAPTPKMNPC1SMN1; SMN2
	SCHEMBL4269871	0.87	SMN1; SMN2 (0.39)	LMNAMAPTPKMMAPK1CASP1
	SCHEMBL19194835	0.87	KDM4E (0.40)	LMNAMAPTPKMMAPK1CASP1
	SCHEMBL4280815	0.86	PDE4B (0.39)	LMNAPKMMAPK1CASP1SMN1; SMN2
	SCHEMBL4269872	0.85	SMN1; SMN2 (0.42)	LMNAMAPTPKMMAPK1CASP1
	SCHEMBL4281121	0.85	S1PR1 (0.43)	S1PR1S1PR3PDE4APDE4BPDE4C
	SCHEMBL4280728	0.85	GSK3B (0.41)	LMNANPC1KDM4EALDH1A1HPGD
	SCHEMBL4271650	0.83	RAB9A (0.41)	NPC1SMN1; SMN2KDM4ECYP19A1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.