SCHEMBL4281121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4277016	0.95	S1PR1 (0.45)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4270719	0.90	S1PR1 (0.44)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4271297	0.90	S1PR1 (0.43)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4279424	0.89	PDE4A (0.44)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4280815	0.88	PDE4B (0.39)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4284194	0.87	PDE4A (0.45)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL4270628	0.85	S1PR1 (0.43)	S1PR1S1PR3MEN1KMT2A
	SCHEMBL4277625	0.85	LMNA (0.36)	S1PR1S1PR3PDE4APDE4DPDE4B
	SCHEMBL19194835	0.85	KDM4E (0.40)	MEN1KMT2A
	SCHEMBL4269871	0.85	SMN1; SMN2 (0.39)	S1PR1S1PR3PDE4BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.