Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933420 | 0.85 | CA12 (0.57) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL951002 | 0.82 | ALDH1A1 (0.50) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL4148206 | 0.81 | ALDH1A1 (0.41) | CA2CA12CA9CA1TRPA1 | |
| SCHEMBL18130115 | 0.81 | FFAR1 (0.40) | CA2CA12CA9CA1TRPA1 | |
| SCHEMBL18130071 | 0.81 | KCNH2 (0.44) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL29640432 | 0.81 | APP (0.58) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL28272577 | 0.78 | CA12 (0.61) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL29640438 | 0.75 | TP53 (0.50) | CA2CA1FFAR1ALDH1A1LMNA | |
| SCHEMBL9445826 | 0.72 | GRM5 (0.64) | CA2CA12CA9KCNH2CA1 | |
| SCHEMBL4457730 | 0.72 | GRM5 (0.64) | CA2CA12CA9KCNH2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126700-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS AS COSMETICS OR THERAPEUTICS FOR SKIN CONDITIONS | KENT STATE UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |