SCHEMBL427788

SCHEMBL427788

CCCn1cc[n+](C)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 4/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
POLB P06746 1/20 0.33
APOBEC3A P31941 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
PLA2G1B P04054 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427605 0.88 KMT2A (0.39) HDAC8HTTSMN1; SMN2LMNAHPGD
SCHEMBL424958 0.83
SCHEMBL424276 0.79 HDAC8 (0.36) HDAC8MEN1KMT2AACHE
SCHEMBL319282 0.77 ACHE (0.45) HDAC8HTTSMN1; SMN2LMNAHPGD
SCHEMBL28938343 0.77 HDAC8 (0.52) HDAC8HTTSMN1; SMN2LMNAHPGD
Hydrochloric Acid SCHEMBL1884666 0.75 ACHE (0.47) HDAC8HTTSMN1; SMN2LMNAHPGD
Fluoride Ion SCHEMBL21980194 0.75 ACHE (0.44) HDAC8HTTSMN1; SMN2LMNAHPGD
Water SCHEMBL15365841 0.75 ACHE (0.44) HDAC8HTTSMN1; SMN2LMNAHPGD
SCHEMBL5330262 0.75 HDAC8 (0.35) HDAC8HTTSMN1; SMN2LMNAHPGD
Bromide SCHEMBL8204076 0.75 CA1 (0.44) HDAC8HTTSMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981034-B1 ACTUATOR ELEMENT DAIKIN IND LTD (JP) 2016-01-13 EP disclosed
US-8637601-B2 Fluorine-containing polymer having heteroaromatic ring DAIKIN INDUSTRIES, LTD. (JP) 2014-01-28 US disclosed
US-8545732-B2 Electrode film for polymer actuator element, and polymer actuator element comprising the same DAIKIN INDUSTRIES, LTD. (JP) 2013-10-01 US disclosed
EP-1983008-B1 FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING DAIKIN IND LTD (JP) 2012-12-26 EP disclosed
US-20120271005-A1 FLUORINE-CONTAINING POLYMER HAVING HETEROAROMATIC RING DAIKIN INDUSTRIES, LTD. (JP) 2012-10-25 US disclosed
US-8236887-B2 Fluorine-containing polymer having heteroaromatic ring DAIKIN INDUSTRIES, LTD. (JP) 2012-08-07 US disclosed
US-8123983-B2 Actuator element DAIKIN INDUSTRIES, LTD. (JP) 2012-02-28 US disclosed
EP-2416488-A1 ELECTRODE FILM FOR POLYMER ACTUATOR ELEMENT, AND POLYMER ACTUATOR ELEMENT COMPRISING SAME Daikin Industries, Ltd. (JP) 2012-02-08 EP disclosed
US-20120018680-A1 ELECTRODE FILM FOR POLYMER ACTUATOR ELEMENT, AND POLYMER ACTUATOR ELEMENT COMPRISING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHONOLGY (JP) 2012-01-26 US disclosed
US-20100164330-A1 ACTUATOR ELEMENT DAIKIN INDUSTRIES, LTD (JP) 2010-07-01 US disclosed
US-20090105400-A1 Imidazolium side chains for example; for example polymers based on 1-methyl-3-(2H,9H,9H-perfluoro-3,6-dioxa-5-methyl-8-nonenyl)-imidazolium trifluoromethanesulfonate; polymer electrolytes for fuel cell, secondary battery, capacitor, dye-sensitized solar cell and electrochromic device DAIKIN INDUSTRIES, LTD. (JP) 2009-04-23 US disclosed
EP-1983008-A1 FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING Daikin Industries, Ltd. (JP) 2008-10-22 EP disclosed
EP-1981034-A1 ACTUATOR ELEMENT Daikin Industries, Ltd. (JP) 2008-10-15 EP disclosed