Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | EEF2K | O00418 | 2/20 | 0.37 |
| ▸ | EEF2 | P13639 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319282 | 0.98 | ACHE (0.45) | CA1CA2ACHEEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL1884666 | 0.96 | ACHE (0.47) | CA1CA2ACHEEEF2KEEF2 | |
| Iodide SCHEMBL302515 | 0.96 | ACHE (0.44) | CA1CA2ACHEEEF2KEEF2 | |
| Fluoride Ion SCHEMBL21980194 | 0.96 | ACHE (0.44) | CA1CA2ACHEEEF2KEEF2 | |
| Water SCHEMBL15365841 | 0.96 | ACHE (0.44) | CA1CA2ACHEEEF2KEEF2 | |
| SCHEMBL15732265 | 0.90 | ACHE (0.41) | CA1CA2ACHEEEF2KEEF2 | |
| SCHEMBL15348251 | 0.90 | ACHE (0.41) | CA1CA2ACHEEEF2KEEF2 | |
| SCHEMBL28698375 | 0.90 | ACHE (0.41) | CA1CA2ACHEEEF2KEEF2 | |
| SCHEMBL61367 | 0.90 | LMNA (0.42) | CA1CA2ACHEEEF2KEEF2 | |
| Bromide SCHEMBL711969 | 0.88 | CA1 (0.49) | CA1CA2ACHEEEF2KEEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240009613-A1 | CO2 CAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES | AGARWAL, Shantanu | 2024-01-11 | — | — | US | claimed |
| EP-4196246-A1 | <SUP2/>? <SUB2/>?2?COCAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES | Susteon Inc. (US) | 2023-06-21 | — | — | EP | claimed |
| CN-114853716-A | Technology and device for efficiently synthesizing alcohol esters by carbon dioxide | 北京石大油源科技开发有限公司 | 2022-08-05 | — | — | CN | claimed |
| WO-2022040072-A1 | CO2 CAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES | SUSTEON INC. (US) | 2022-02-24 | — | — | WO | claimed |
| US-11258100-B2 | Electrolyte composition and metal-ion battery employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INTITUTE (TW) | 2022-02-22 | — | — | US | claimed |
| CN-111224163-B | Electrolyte composition and metal ion battery comprising same | 财团法人工业技术研究院 | 2022-02-22 | — | — | CN | claimed |
| CN-111224163-A | Electrolyte composition and metal ion battery comprising same | 财团法人工业技术研究院 | 2020-06-02 | — | — | CN | claimed |
| US-20200168954-A1 | ELECTROLYTE COMPOSITION AND METAL-ION BATTERY EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-05-28 | — | — | US | claimed |
| US-9932287-B2 | Process for oxidation of alkyl aromatic compound to aromatic carboxylic acid | RELIANCE INDUSTRIES LIMITED (IN) | 2018-04-03 | — | — | US | claimed |
| EP-3107886-B1 | PROCESS FOR OXIDATION OF ALKYL AROMATIC COMPOUND TO AROMATIC CARBOXYLIC ACID | RELIANCE INDUSTRIES LTD (IN) | 2018-03-28 | — | — | EP | claimed |
| EP-3107886-A1 | PROCESS FOR OXIDATION OF ALKYL AROMATIC COMPOUND TO AROMATIC CARBOXYLIC ACID | Reliance Industries Limited (IN) | 2016-12-28 | — | — | EP | claimed |
| US-20160347700-A1 | PROCESS FOR OXIDATION OF ALKYL AROMATIC COMPOUND TO AROMATIC CARBOXYLIC ACID | RELIANCE INDUSTRIES LIMITED (IN) | 2016-12-01 | — | — | US | claimed |
| WO-2015125095-A1 | PROCESS FOR OXIDATION OF ALKYL AROMATIC COMPOUND TO AROMATIC CARBOXYLIC ACID | RELIANCE INDUSTRIES LIMITED (IN) | 2015-08-27 | — | — | WO | claimed |
| US-20240009613-A1 | CO2 CAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES | AGARWAL, Shantanu | 2024-01-11 | — | — | US | disclosed |
| EP-4196246-A1 | <SUP2/>? <SUB2/>?2?COCAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES | Susteon Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| CN-114853716-A | Technology and device for efficiently synthesizing alcohol esters by carbon dioxide | 北京石大油源科技开发有限公司 | 2022-08-05 | — | — | CN | disclosed |
| US-20130309679-A1 | FLUIDIC DEVICES AND SYSTEMS FOR SAMPLE PREPARATION OR AUTONOMOUS ANALYSIS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130280725-A1 | FLUIDIC DEVICES FOR BIOSPECIMEN PRESERVATION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281316-A1 | SLIP-INDUCED COMPARTMENTALIZATION | SlipChip, LLC (US) | 2013-10-24 | — | — | US | disclosed |
| US-6025457-A | POLYMERIZABLE IMIDAZOLIUM DERIVATIVE; HEAT RESISTANCE | SHIKOKU CHEMICALS CORPORATION (JP) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11258100-B2 | Electrolyte composition and metal-ion battery employing the same | SLC26A3, F8, CLIC1 | ACHE 615/4885CA1 62/4885CA2 18/4885 |
| US-20200168954-A1 | ELECTROLYTE COMPOSITION AND METAL-ION BATTERY EMPLOYING THE SAME | SLC26A3, F8, CLIC1 | ACHE 615/4885CA1 62/4885CA2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.