SCHEMBL4278093

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4279234	0.94	MAPT (0.51)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL4280194	0.91	KCNH2 (0.67)	KCNH2CACNA1ICACNA1HCYP2D6
	SCHEMBL4273051	0.90	KCNH2 (0.58)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL4277726	0.90	GSK3B (0.48)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL4269219	0.90	KCNH2 (0.57)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL8374137	0.90	CACNA1H (0.49)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL20056299	0.90	GSK3B (0.48)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL4273172	0.90	KCNH2 (0.57)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL14706527	0.88	GSK3B (0.46)	KCNH2CACNA1IGSK3BCACNA1HCYP2D6
	SCHEMBL4284138	0.87	KCNH2 (0.60)	KCNH2CACNA1ICACNA1HCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.