Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 11/20 | 0.99 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.58 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4284849 | 0.99 | SLC2A1 (1.00) | SLC2A1KCNH2CCR8 | |
| SCHEMBL4276893 | 0.90 | SLC2A1 (0.81) | SLC2A1KCNH2CCR8 | |
| SCHEMBL27577361 | 0.87 | SLC2A1 (0.77) | SLC2A1KCNH2CCR8 | |
| SCHEMBL4279724 | 0.87 | SLC2A1 (0.75) | SLC2A1KCNH2 | |
| SCHEMBL7170541 | 0.87 | SLC2A1 (0.75) | SLC2A1KCNH2 | |
| SCHEMBL4269307 | 0.87 | SLC2A1 (0.77) | SLC2A1KCNH2CCR8 | |
| SCHEMBL13857004 | 0.83 | SLC2A1 (0.71) | SLC2A1KCNH2 | |
| SCHEMBL4273761 | 0.82 | SLC2A1 (0.69) | SLC2A1KCNH2 | |
| SCHEMBL4273771 | 0.82 | SLC2A1 (0.69) | SLC2A1KCNH2 | |
| SCHEMBL4273779 | 0.82 | SLC2A1 (0.69) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | claimed |
| US-20060014749-A1 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. | 2006-01-19 | — | — | US | claimed |
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | disclosed |
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014749-A1 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | AZI2, NPEPPS, AMPD2 | SLC2A1 3675/4885KCNH2 785/4885CCR8 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.