Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 3/20 | 0.40 |
| ▸ | GSTA2 | P09210 | 2/20 | 0.36 |
| ▸ | GSTM1 | P09488 | 2/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657214 | 1.00 | GSTP1 (0.40) | GSTP1GSTA2GSTM1SSTR1SSTR2 | |
| SCHEMBL582951 | 0.90 | MEN1 (0.32) | GSTP1PDPK1MTOR | |
| SCHEMBL7458038 | 0.84 | TACR1 (0.36) | — | |
| SCHEMBL583131 | 0.83 | TACR1 (0.34) | — | |
| SCHEMBL5017349 | 0.80 | GSTP1 (0.51) | GSTP1GSTA2GSTM1SSTR1SSTR2 | |
| SCHEMBL14094693 | 0.80 | GSTP1 (0.51) | GSTP1GSTA2GSTM1SSTR1SSTR2 | |
| SCHEMBL13657211 | 0.80 | GSTP1 (0.32) | GSTP1GSTA2GSTM1 | |
| SCHEMBL4279232 | 0.80 | GSTP1 (0.32) | GSTP1GSTA2GSTM1 | |
| SCHEMBL5691292 | 0.78 | L3MBTL1 (0.35) | PDPK1MTOR | |
| SCHEMBL13858947 | 0.78 | PDPK1 (0.40) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605241-B2 | Synthesis of inhibitors of p90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | RAF1, KSR1, STK10 | GSTP1 2365/4885GSTA2 3896/4885GSTM1 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.