SCHEMBL4279372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15521504	0.94	NOS3 (0.35)	PDE4ALMNAPDE4BPDE4CPDE4D
	SCHEMBL17243834	0.92	PDE4B (0.33)	PDE4ALMNAPDE4BPDE4CPDE4D
	SCHEMBL24297133	0.88	PTPN11 (0.35)	LMNAPDE4DMAPK1ABCB1ABCC1
	SCHEMBL15521511	0.88	DHODH (0.37)	PDE4ALMNAPDE4BPDE4CPDE4D
	Hydrochloric Acid SCHEMBL30484503	0.87	ALDH1A1 (0.39)	PDE4ALMNAPDE4BPDE4CPDE4D
	SCHEMBL29813303	0.86	PTPN11 (0.39)	PDE4ALMNAPDE4BPDE4CPDE4D
	SCHEMBL8231093	0.86	PTPN11 (0.39)	PDE4ALMNAPDE4BPDE4CPDE4D
	SCHEMBL4284397	0.86	TSHR (0.44)	LMNAPDE4BHPGDTSHRSMN1; SMN2
	SCHEMBL4280199	0.86	TSHR (0.41)	LMNAPDE4BHPGDTSHRSMN1; SMN2
	SCHEMBL19066427	0.86	TSHR (0.41)	LMNAPDE4BHPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.