Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279479 | 1.00 | DRD2 (0.51) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL4051485 | 0.79 | KDM4E (0.58) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL29673233 | 0.79 | DRD2 (0.55) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL18175179 | 0.79 | DRD2 (0.55) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL29779540 | 0.79 | KDM4E (0.58) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL30263125 | 0.78 | KDM4E (0.57) | DRD2DRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL773530 | 0.75 | PNMT (0.49) | DRD2 | |
| SCHEMBL773531 | 0.75 | PNMT (0.49) | DRD2 | |
| SCHEMBL772706 | 0.75 | PLAU (0.49) | DRD2PLAU | |
| SCHEMBL772707 | 0.75 | PLAU (0.49) | DRD2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151621-A1 | SUBSTITUTED (1, 2, 4-0XADIAZ0L-3-YL) INDOLIN-1-YL CARBOXYLIC ACID DERIVATIVES USEFUL AS S1P1 AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |