Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | USP7 | Q93009 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16432654 | 0.99 | FAAH (0.52) | FAAHCES2KCNH2KIF11USP7 | |
| SCHEMBL17828659 | 0.91 | FAAH (0.53) | FAAHCES2KCNH2KIF11MCHR1 | |
| SCHEMBL427429 | 0.89 | FAAH (0.59) | FAAHCES2KCNH2KIF11CHRM1 | |
| SCHEMBL427874 | 0.89 | FAAH (0.64) | FAAHCES2FYNALDH1A1HPGD | |
| SCHEMBL16433307 | 0.89 | FAAH (0.54) | FAAHCES2KCNH2KIF11FYN | |
| SCHEMBL425914 | 0.88 | FAAH (0.66) | FAAHCES2FYNALDH1A1HPGD | |
| Bromide SCHEMBL17819169 | 0.88 | FAAH (0.53) | FAAHCES2KCNH2KIF11FYN | |
| SCHEMBL17853478 | 0.87 | FAAH (0.50) | FAAHCES2KCNH2KIF11MCHR1 | |
| SCHEMBL16439301 | 0.87 | FAAH (0.50) | FAAHCES2MCHR1KDM4EALDH1A1 | |
| SCHEMBL425329 | 0.87 | FAAH (0.50) | FAAHCES2MCHR1TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | BIAL-PORTELA & CA, S.A. (PT) | 2016-06-16 | — | — | US | disclosed |
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | BIAL-PORTELA & CA, S.A. (PT) | 2016-06-16 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| CN-105593226-A | Urea compounds and their use as FAAH enzyme inhibitors | BIAL-PORTELA & CA S A | 2016-05-18 | — | — | CN | disclosed |
| WO-2015016728-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | FAAH 1/4885CES2 62/4885KCNH2 1739/4885 |
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | FAAH, FAAH2, HRH2 | FAAH 1/4885CES2 33/4885KCNH2 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.