SCHEMBL4280640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4283990	0.89	CACNA1I (0.52)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL8374110	0.89	CACNA1I (0.52)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL4277984	0.89	CACNA1I (0.66)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL4273162	0.88	KMT2A (0.59)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL4272435	0.86	CACNA1I (0.55)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL26082500	0.86	CACNA1I (0.70)	CACNA1IKCNH2CACNA1GCACNA1H
	SCHEMBL4282288	0.85	CCR2 (0.59)	CCR2CACNA1IKCNH2SMN1; SMN2CACNA1G
	SCHEMBL4282283	0.83	CACNA1I (0.53)	CACNA1IKCNH2SMN1; SMN2CACNA1GCACNA1H
	SCHEMBL4279227	0.83	CCR2 (0.49)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL4276609	0.81	CACNA1I (0.72)	CACNA1IKCNH2CACNA1GCACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.