SCHEMBL4280751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273489	0.94	S1PR1 (0.41)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL4276119	0.94	CTNNB1 (0.41)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL13701426	0.92	S1PR1 (0.43)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL4271153	0.90	SMN1; SMN2 (0.39)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL4275723	0.90	S1PR1 (0.38)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL4271280	0.89	CAPN1 (0.39)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL19199080	0.89	S1PR1 (0.39)	S1PR1S1PR3S1PR5CTNNB1WNT3A
	SCHEMBL4282846	0.88	MAPT (0.41)	S1PR1S1PR3S1PR5PTGS2KDM4E
	SCHEMBL4278360	0.88	PTGS2 (0.44)	S1PR1S1PR3S1PR5PTGS2KDM4E
	SCHEMBL4271262	0.88	LCLAT1 (0.39)	S1PR1S1PR3S1PR5CTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.