SCHEMBL4282846

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273489	0.93	S1PR1 (0.41)	MAPTSMN1; SMN2MEN1KMT2AS1PR1
	SCHEMBL4276119	0.93	CTNNB1 (0.41)	MAPTSMN1; SMN2MEN1KMT2AS1PR1
	SCHEMBL4278360	0.91	PTGS2 (0.44)	MAPTSMN1; SMN2MEN1KMT2AS1PR1
	SCHEMBL13701426	0.91	S1PR1 (0.43)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4270475	0.89	IDO1 (0.41)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4281082	0.88	MAPT (0.43)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4271153	0.88	SMN1; SMN2 (0.39)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4280751	0.88	S1PR1 (0.38)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4275723	0.88	S1PR1 (0.38)	MAPTSMN1; SMN2ALDH1A1GAAS1PR1
	SCHEMBL8237292	0.88	SMN1; SMN2 (0.43)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.