Glycylleucylphenylalanine

Glycylleucylphenylalanine

SCHEMBL4281374

CC(C)C[C@H](NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.62
MMP2 P08253 1/20 0.61
MMP7 P09237 1/20 0.61
MMP9 P14780 1/20 0.61
MMP12 P39900 1/20 0.61
MMP13 P45452 1/20 0.61
MME P08473 3/20 0.61
CPA1 P15085 1/20 0.57
ACE2 Q9BYF1 1/20 0.57
CTSB P07858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycylleucylphenylalanine SCHEMBL4281369 1.00 ACE (0.62) ACEMMP2MMP7MMP9MMP12
SCHEMBL21192616 0.95 ACE (0.57) ACEMMP2MMP7MMP9MMP12
SCHEMBL21192611 0.95 ACE (0.57) ACEMMP2MMP7MMP9MMP12
SCHEMBL9551455 0.95 MME (0.64) ACEMMP2MMP7MMP9MMP12
SCHEMBL5370772 0.95 MME (0.64) ACEMMP2MMP7MMP9MMP12
SCHEMBL9829182 0.95 MME (0.64) ACEMMP2MMP7MMP9MMP12
SCHEMBL30396564 0.93 ACE (0.63) ACEMMP2MMP7MMP9MMP12
SCHEMBL8983297 0.92 CTSB (0.62) ACEMMP2MMP7MMP9MMP12
SCHEMBL8983313 0.92 CTSB (0.62) ACEMMP2MMP7MMP9MMP12
SCHEMBL29427560 0.92 MME (0.58) ACEMMP2MMP7MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3227 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111051329-B Hamiltelin derivatives and their antibody drug complexes 住友制药株式会社 2024-07-30 CN claimed
CN-117230048-A Threonine aldolase mutant with improved stereoselectivity and application thereof 浙江工业大学 2023-12-15 CN claimed
US-11801307-B2 Antibody-polymer-drug conjugates UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-10-31 US claimed
EP-4045087-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF University of Utah Research Foundation (US) 2022-08-24 EP claimed
US-20220249682-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION 2022-08-11 US claimed
CN-107513103-B MASP isoforms as inhibitors of complement activation OMEROS CORP. (US) 2026-05-26 CN disclosed
CN-106987570-B Cas9 nuclease R780A and application thereof SHANGHAI JIAO TONG UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-122080238-A RBoNT recombinant protein and precursor thereof, and preparation method and application thereof 2026-05-26 CN disclosed
CN-114080232-B Extracellular vesicles for vaccine delivery Lhasa Sales Co.,Ltd. (CH) 2026-05-26 CN disclosed
CN-116194479-B Anti-TAU antibodies GT创新公司 2026-05-22 CN disclosed
WO-2026107236-A1 COMPOSITIONS AND METHODS FOR VACCINATION AGAINST MYCOBACTERIUM TUBERCULOSIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2026-05-21 WO disclosed
CN-106794263-B Vaccine with antigen and interleukin-21 as adjuvant 宾夕法尼亚大学理事会 2026-05-19 CN disclosed
CN-113969286-A Rice cadmium low-accumulation molecular marker, mutant gene, detection kit, rapid identification method and application thereof, and typing primer 湖南杂交水稻研究中心 2022-01-25 CN disclosed
CN-108138170-B DEPDC 1-derived peptides and vaccines containing the same 肿瘤疗法科学股份有限公司 2022-01-25 CN disclosed
CN-113968911-A insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2022-01-25 CN disclosed
CN-113969290-A Deep sea bacterium-derived alpha-glucosidase QsGH97a and coding gene and application thereof 中南大学 2022-01-25 CN disclosed
CN-107847592-B Antibodies against human CSF-1R for inducing lymphocytosis in lymphomas or leukemias 豪夫迈·罗氏有限公司 2022-01-21 CN disclosed
CN-113957061-A Administration of kynurenine depleting enzymes for tumor therapy 得克萨斯大学体系董事会 2022-01-21 CN disclosed
CN-113956361-A Antibodies to ticagrelor and methods of use thereof 免疫医疗有限公司 2022-01-21 CN disclosed
US-20090143279-A1 Methods and compositions for treating metabolic disorders PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2009-06-04 US disclosed