SCHEMBL5370772

SCHEMBL5370772

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.64
LTA4H P09960 1/20 0.58
ACE P12821 1/20 0.58
MMP2 P08253 1/20 0.58
MMP7 P09237 1/20 0.58
MMP9 P14780 1/20 0.58
MMP12 P39900 1/20 0.58
MMP13 P45452 1/20 0.58
PSMB5 P28074 3/20 0.57
OPRM1 P35372 2/20 0.56
OPRD1 P41143 2/20 0.56
OPRK1 P41145 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551455 1.00 MME (0.64) MMELTA4HACEMMP2MMP7
SCHEMBL9829182 1.00 MME (0.64) MMELTA4HACEMMP2MMP7
SCHEMBL8060317 0.95 MME (0.59) MMELTA4HACEMMP2MMP7
SCHEMBL8060325 0.95 MME (0.59) MMELTA4HACEMMP2MMP7
Glycylleucylphenylalanine SCHEMBL4281374 0.95 ACE (0.62) MMEACEMMP2MMP7MMP9
Glycylleucylphenylalanine SCHEMBL4281369 0.95 ACE (0.62) MMEACEMMP2MMP7MMP9
SCHEMBL29427560 0.94 MME (0.58) MMELTA4HACEMMP2MMP7
SCHEMBL30799577 0.94 MME (0.60) MMELTA4HMMP2MMP7MMP9
SCHEMBL2519495 0.92 ACE (0.56) MMEACEMMP2MMP7MMP9
SCHEMBL5966413 0.92 OPRM1 (0.65) MMEOPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294802-A1 CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF Universität Bielefeld (DE) 2023-12-27 EP claimed
CN-115747058-A Micro-fluidic chip, detection system and surface treatment reagent combination therein 上海柏慧康生物科技有限公司 2023-03-07 CN claimed
WO-2022175222-A1 CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF UNIVERSITÄT BIELEFELD (DE) 2022-08-25 WO claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
WO-2025136369-A1 SAFETY-CATCH LINKERS FOR SOLID PHASE PEPTIDE SYNTHESIS AAPPTec, LLC (US) 2025-06-26 WO disclosed
US-20250197441-A1 Safety-Catch Linkers for Solid Phase Peptide Synthesis AAPPTec, LLC (US) 2025-06-19 US disclosed
WO-2024222960-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF 上海弼领生物技术有限公司 2024-10-31 WO disclosed
EP-4294802-A1 CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF Universität Bielefeld (DE) 2023-12-27 EP disclosed
CN-220176828-U Microchannel reaction device for synthesizing polypeptide 厦门胜泽泰医药科技有限公司 2023-12-15 CN disclosed
US-11793853-B2 Retinylamine derivitives for treatment of ocular disorders CASE WESTERN RESERVE UNIVERSITY (US) 2023-10-24 US disclosed
EP-0604552-B1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS AFFYMAX TECH NV (AN) 1997-02-12 EP disclosed
EP-0754302-A1 METHODS AND APPARATUS FOR SYNTHESIZING LABELED COMBINATORIAL CHEMICAL LIBRARIES ONTOGEN CORPORATION (US) 1997-01-22 EP disclosed
WO-1996024061-A1 METHODS AND APPARATUS FOR SYNTHESIZING LABELED COMBINATORIAL CHEMICAL LIBRARIES ONTOGEN CORPORATION (US) 1996-08-08 WO disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
US-4739076-A WATER SOLUBLE, FOR PEPTIDES AND PROTEINS SOUTHWICK PHILIP L (US) 1988-04-19 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197441-A1 Safety-Catch Linkers for Solid Phase Peptide Synthesis PNISR, SPPL2B, VIP MME 1443/4885LTA4H 3787/4885ACE 1530/4885
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP MME 824/4885LTA4H 3533/4885ACE 1190/4885
US-11793853-B2 Retinylamine derivitives for treatment of ocular disorders LRAT, RBP1, RBP4 MME 1535/4885LTA4H 985/4885ACE 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.