SCHEMBL4281375

SCHEMBL4281375

CCN(C(=S)[S-])c1ccccc1.CCN(C(=S)[S-])c1ccccc1.CCN(C(=S)[S-])c1ccccc1.CCN(C(=S)[S-])c1ccccc1.[Pb+4]

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
GLA P06280 1/20 0.57
TSHR P16473 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
TP53 P04637 2/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21753954 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
SCHEMBL301769 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
SCHEMBL28688718 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
SCHEMBL2021353 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
Lithium Ion SCHEMBL9355932 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
SCHEMBL9355761 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
Potassium Ion SCHEMBL9356007 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
Zinc Ion SCHEMBL78992 0.96 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1CA12
SCHEMBL4603063 0.81 ALDH1A1 (0.63) ALDH1A1GLATSHRL3MBTL1TP53
SCHEMBL1276930 0.81 ALDH1A1 (0.63) ALDH1A1GLATSHRL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852499-B2 Luciferase detection reagent kits and luciferase detection method using the kit TOYO INK MFG. CO., LTD. 2005-02-08 US claimed
EP-1400595-A1 Luciferase detection reagent kits and luciferase detection method using the kits Toyo B-Net Co., Ltd (JP) 2004-03-24 EP claimed
US-4248985-A Sulfur-curable acrylic rubber composition NIPPON ZEON CO., LTD. (JP) 1981-02-03 US claimed
US-4237247-A MERCAPTOTRIAZINE CROSSLINKING AGENT AND A THIURAM SULFIDE ACCELERATOR AND AN ACID ACCEPTOR ALLOW THE USE OF ADDITIVES DURING CURING OSAKA SODA CO. LTD. (JP) 1980-12-02 US claimed
CN-113166356-B Method for producing polyurethane compositions 巴斯夫欧洲公司 2023-12-29 CN disclosed
US-20210380750-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2021-12-09 US disclosed
EP-3887420-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2021-10-06 EP disclosed
CN-113166356-A Process for producing polyurethane composition 巴斯夫欧洲公司 2021-07-23 CN disclosed
WO-2020109366-A1 PROCESS FOR PRODUCING A POLYURETHANE COMPOSITION BASF SE (DE) 2020-06-04 WO disclosed
EP-3023446-A1 Continuous high-throughput process for the preparation of polyurethanes BASF SE (DE) 2016-05-25 EP disclosed
EP-2517900-B1 Laminated body and method of producing the same as well as innerliner for pneumatic tire and pneumatic tire BRIDGESTONE CORP (JP) 2014-04-23 EP disclosed
EP-1876195-B1 Polymerization Process ROHM & HAAS (US) 2013-05-01 EP disclosed
US-5466757-A Thiourea and sulfur donors with metal compounds for curing and vulcanization SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-11-14 US disclosed
EP-0268457-B1 PROCESS FOR PRODUCTION OF CHLORINATED ETHYLENE-PROPYLENE COPOLYMERS SHOWA DENKO KABUSHIKI KAISHA (JP) 1993-01-20 EP disclosed
US-5087673-A Chlorination in aqueous suspension; controlling temperature SHOWA DENKO K.K. (JP) 1992-02-11 US disclosed
EP-0268457-A2 Process for production of chlorinated ethylene-propylene copolymers SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-05-25 EP disclosed
US-4547554-A After-chlorinated ethylene/butene-1 copolymer and process for its production OSAKA SODA CO., LTD. (JP) 1985-10-15 US disclosed
US-4248985-A Sulfur-curable acrylic rubber composition NIPPON ZEON CO., LTD. (JP) 1981-02-03 US disclosed
US-4237247-A MERCAPTOTRIAZINE CROSSLINKING AGENT AND A THIURAM SULFIDE ACCELERATOR AND AN ACID ACCEPTOR ALLOW THE USE OF ADDITIVES DURING CURING OSAKA SODA CO. LTD. (JP) 1980-12-02 US disclosed
US-4165416-A INCLUDING A MERCAPTOTRIAZINE CROSSLINKING AGENT, AN AMINE ACCELERATORS AN ACID ACCEPTOR OF METAL COMPOUNDS AND A PLASTICIZER AND REINFORCEMENT AGENT OSAKA SODA CO. LTD. (JP) 1979-08-21 US disclosed