Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518982 | 0.81 | ALOX5 (0.51) | ALOX5DAOMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5926065 | 0.81 | GABBR2 (0.47) | ALOX5DAOSLC7A5SMN1; SMN2KMT2A | |
| SCHEMBL4632227 | 0.77 | CYP2C9 (0.54) | ALOX5DAOMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5521073 | 0.74 | ALOX5 (0.49) | ALOX5DAOMAPTSMN1; SMN2NPC1 | |
| SCHEMBL21339011 | 0.73 | ALOX5 (0.45) | ALOX5DAOMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12261660 | 0.72 | — | — | |
| SCHEMBL506526 | 0.72 | — | — | |
| SCHEMBL8737184 | 0.72 | ALOX5 (0.44) | ALOX5DAOMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11697031 | 0.72 | ALOX5 (0.54) | ALOX5DAOMAPTSMN1; SMN2KDM4E | |
| SCHEMBL1520622 | 0.71 | ALOX5 (0.46) | ALOX5DAOMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121496-A2 | USE OF A BIOLOGICALLY ACTIVE BLOOD SERUM FOR THE TREATMENT OF A DISORDER CHARCTERIZED IN A REDUCED FUNCTION OF A GABA RECEPTOR | OWEN HOLDING LTD. (GB) | 2009-10-08 | — | — | WO | claimed |