Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279635 | 0.95 | CYP3A4 (0.50) | CYP3A4LMNAMTNR1AMTNR1BACHE | |
| SCHEMBL1790266 | 0.86 | PPARA (0.57) | CYP3A4LMNAMTNR1AMTNR1BACHE | |
| SCHEMBL4268403 | 0.86 | CYP3A4 (0.53) | CYP3A4LMNAMTNR1AMTNR1BACHE | |
| SCHEMBL4282042 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BACHEPPARGPPARA | |
| SCHEMBL27865972 | 0.84 | PPARA (0.63) | CYP3A4LMNAMTNR1AMTNR1BPPARG | |
| SCHEMBL4268393 | 0.84 | CYP4F2 (0.56) | CYP3A4LMNAMTNR1AMTNR1BACHE | |
| SCHEMBL30631323 | 0.84 | PPARA (0.63) | CYP3A4LMNAMTNR1AMTNR1BPPARG | |
| SCHEMBL12648662 | 0.83 | CYP3A4 (0.58) | CYP3A4LMNAACHEPARP1 | |
| SCHEMBL1517301 | 0.83 | PPARA (0.66) | PPARGPPARAHDAC1HDAC6 | |
| SCHEMBL5280181 | 0.83 | CYP3A4 (0.50) | CYP3A4LMNAMTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9627204-B2 | Composition for forming a coating type BPSG film, substrate formed a film by said composition, and patterning process using said composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |