Guanidine

Guanidine

SCHEMBL4282132

Cl.Cl.Cl.Cl.N=C(N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL29088714 1.00 NOS2 (0.39)
Guanidine SCHEMBL5053878 1.00 NOS2 (0.39)
Guanidine SCHEMBL28377118 1.00 NOS2 (0.39)
Guanidine SCHEMBL2453389 1.00
Guanidine SCHEMBL8024162 1.00
Guanidine SCHEMBL17184362 1.00 NOS2 (0.39)
Guanidine SCHEMBL3349156 1.00
Guanidine SCHEMBL19610646 1.00 NOS2 (0.39)
Guanidine SCHEMBL395351 1.00 NOS2 (0.39)
Guanidine SCHEMBL28140556 1.00 NOS2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115128147-B Rapid analysis method for fusion protein sample 盛禾(中国)生物制药有限公司 2025-02-11 CN claimed
CN-115078728-B Rapid analysis method of fusion protein 盛禾(中国)生物制药有限公司 2024-10-22 CN claimed
CN-115128147-A Rapid analysis method of fusion protein sample 盛禾(中国)生物制药有限公司 2022-09-30 CN claimed
CN-115078728-A Rapid analysis method of fusion protein 盛禾(中国)生物制药有限公司 2022-09-20 CN claimed
CN-105725183-A Fish bone glue and preparation method thereof 佛山市聚成生化技术研发有限公司 2016-07-06 CN claimed
CN-105639658-A Bone collagen and preparation method thereof 佛山市聚成生化技术研发有限公司 2016-06-08 CN claimed
CN-103088096-A Method for extracting collagen type II by taking agkistrodon as raw material UNIV ZHEJIANG CHINESE MEDICAL 2013-05-08 CN claimed
CN-103060415-A Preparation method of collagen for treating rheumatic arthritis QINGDAO BETTER BIO TECHNOLOGY CO LTD 2013-04-24 CN claimed
CN-101570772-B Method for preparing natural ossein CHINA MEAT RES CT 2012-07-25 CN claimed
CN-101570772-A Method for preparing natural ossein CHINA MEAT RES CT (CN) 2009-11-04 CN claimed
CN-115128147-B Rapid analysis method for fusion protein sample 盛禾(中国)生物制药有限公司 2025-02-11 CN disclosed
CN-115078728-B Rapid analysis method of fusion protein 盛禾(中国)生物制药有限公司 2024-10-22 CN disclosed
CN-117625740-A Method for rapidly extracting DNA suitable for high-throughput sequencing from Trizol sample 嘉应学院 2024-03-01 CN disclosed
CN-115128147-A Rapid analysis method of fusion protein sample 盛禾(中国)生物制药有限公司 2022-09-30 CN disclosed
CN-115078728-A Rapid analysis method of fusion protein 盛禾(中国)生物制药有限公司 2022-09-20 CN disclosed
CN-103088096-A Method for extracting collagen type II by taking agkistrodon as raw material UNIV ZHEJIANG CHINESE MEDICAL 2013-05-08 CN disclosed
CN-103060415-A Preparation method of collagen for treating rheumatic arthritis QINGDAO BETTER BIO TECHNOLOGY CO LTD 2013-04-24 CN disclosed
CN-101570772-B Method for preparing natural ossein CHINA MEAT RES CT 2012-07-25 CN disclosed
CN-101570772-A Method for preparing natural ossein CHINA MEAT RES CT (CN) 2009-11-04 CN disclosed
US-20090136929-A1 NOVEL IN VITRO METHOD OF QUANTIFYING DEMINERALIZED BONE OSTEOINDUCTIVITY ZIMMER ORTHOBIOLOGICS, INC. (US) 2009-05-28 US disclosed