Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842230 | 0.81 | ALDH1A1 (0.46) | AKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL6142433 | 0.78 | AKT1 (0.37) | AKT1ALDH1A1ALOX15CYP3A4MAPK1 | |
| SCHEMBL5263569 | 0.76 | — | — | |
| SCHEMBL2038399 | 0.76 | CYP2C19 (0.31) | ALDH1A1CYP3A4MEN1EGFRKMT2A | |
| SCHEMBL143892 | 0.75 | ALDH1A1 (0.38) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| SCHEMBL5138935 | 0.75 | CYP3A4 (0.34) | AKT1ALDH1A1ALOX15CYP3A4MAPK1 | |
| SCHEMBL8965816 | 0.73 | MAPT (0.56) | ALDH1A1CYP3A4MAPK1TDP1KDM4E | |
| SCHEMBL8965807 | 0.73 | MAPT (0.56) | ALDH1A1CYP3A4MAPK1TDP1KDM4E | |
| SCHEMBL11324395 | 0.73 | — | — | |
| SCHEMBL1809 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2698413-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2016-12-28 | — | — | EP | claimed |
| EP-2303987-B9 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-09-10 | — | — | EP | claimed |
| EP-2303987-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-03-26 | — | — | EP | claimed |
| EP-2303988-B9 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2013-12-25 | — | — | EP | claimed |
| EP-2303988-B1 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2013-09-04 | — | — | EP | claimed |
| JP-63125503-A | — | — | None | — | — | JP | disclosed |
| CN-112437890-B | Antireflection film, polarizing plate and display device | 株式会社LG化学 | 2022-12-30 | — | — | CN | disclosed |
| EP-2370420-B9 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2370420-B1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-05-22 | — | — | EP | disclosed |
| CN-105541742-B | A kind of preparation method of ezetimibe intermediate | 江苏恒盛药业有限公司 | 2018-10-26 | — | — | CN | disclosed |
| US-20180291009-A1 | Photochromic Compounds | TRANSITIONS OPTICAL, INC. | 2018-10-11 | — | — | US | disclosed |
| CN-102112465-B | Crystalline forms of 6- [ (4S) -2-methyl-4- (2-naphthyl) -1,2,3, 4-tetrahydroisoquinolin-7-yl ] pyridazin-3-amine | BRISTOL MYERS SQUIBB CO | 2014-09-24 | — | — | CN | disclosed |
| EP-1236731-A1 | Method and apparatus for forming a carbon-silicon bond in a silane | GENERAL ELECTRIC COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| CN-1337013-A | Photosensitive composition, and optical waveguide element and process for producing the same | NIPPON SHEET GLASS CO LTD (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-1154323-A1 | PHOTOSENSITIVE COMPOSITION, AND OPTICAL WAVEGUIDE ELEMENT AND PROCESS FOR PRODUCING THE SAME | Nippon Sheet Glass Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0602154-B1 | SELECTIVE AFFINITY MATERIAL, PREPARATION THEREOF BY MOLECULAR IMPRINTING, AND USE OF THE SAME | GLAD MAGNUS (SE) | 1999-01-27 | — | — | EP | disclosed |
| EP-0602154-A1 | SELECTIVE AFFINITY MATERIAL, PREPARATION THEREOF BY MOLECULAR IMPRINTING, AND USE OF THE SAME | GLAD, Magnus (SE) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005068-A1 | SELECTIVE AFFINITY MATERIAL, PREPARATION THEREOF BY MOLECULAR IMPRINTING, AND USE OF THE SAME | GLAD MAGNUS (SE) | 1993-03-18 | — | — | WO | disclosed |
| JP-S63125503-A | RADICAL-CURABLE COPOLYMER RESIN AND ITS COMPOSITION AND PREPARATION | SHOWA DENKO KK | 1988-05-28 | — | — | JP | disclosed |
| US-4207200-A | Soluble complex former for the affinity specific separation of macromolecular substances, its preparation and its use | BUNEMANN HANS (DE) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180291009-A1 | Photochromic Compounds | CCR4, CCR8, CBR3 | AKT1 3869/4885ALDH1A1 1831/4885ALOX15 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.