SCHEMBL8965807

SCHEMBL8965807

O=C(/C=C/c1ccccc1)c1[c]cccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
CYP1B1 Q16678 6/20 0.56
LMNA P02545 3/20 0.56
PLIN1 O60240 2/20 0.56
RECQL P46063 2/20 0.56
PLIN5 Q00G26 2/20 0.56
ABHD5 Q8WTS1 2/20 0.56
BCHE P06276 2/20 0.56
MAOB P27338 2/20 0.56
TNFRSF1A P19438 1/20 0.56
ACHE P22303 1/20 0.56
F3 P13726 2/20 0.52
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
TNKS O95271 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965816 1.00 MAPT (0.56) MAPTCYP1B1LMNAPLIN1RECQL
SCHEMBL25223319 0.88 CYP3A4 (0.58) MAPTCYP1B1LMNAMAOBF3
SCHEMBL11842230 0.75 ALDH1A1 (0.46) ALDH1A1TDP1MAPK1
SCHEMBL9584825 0.75 NPC1 (0.60) MAPTLMNAPLIN1RECQLPLIN5
SCHEMBL9584820 0.75 NPC1 (0.60) MAPTLMNAPLIN1RECQLPLIN5
SCHEMBL2038399 0.74 CYP2C19 (0.31) LMNAALDH1A1CYP2C9MEN1KMT2A
SCHEMBL6888203 0.73 LMNA (0.38) MAPTCYP1B1LMNAPLIN1RECQL
SCHEMBL4282153 0.73 AKT1 (0.48) MAPTALDH1A1CYP2C9SMN1; SMN2TDP1
SCHEMBL3418546 0.73 CYP1B1 (0.75) MAPTCYP1B1LMNAPLIN1RECQL
SCHEMBL3418544 0.73 CYP1B1 (0.75) MAPTCYP1B1LMNAPLIN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096845-B1 NOVEL COPOLYMER AND PHOTOSENSITIVE MATERIAL CONTAINING THE SAME Daikin Kogyo Co., Ltd. (JP) 1986-09-10 EP claimed
US-4529783-A Fluorine containing acrylic monomer DAIKIN KOGYO COMPANY, LTD. (JP) 1985-07-16 US claimed
EP-0040841-B1 PHOTOSENSITIVE MATERIAL Daikin Kogyo Co., Ltd. (JP) 1985-03-13 EP claimed
US-4424325-A COPOLYMER OF PERFLUOROALKYL OR PERFLUOROALKENYL ACRYLIC MONOMER DAIKIN KOGYO CO., LTD. (JP) 1984-01-03 US claimed
EP-0096845-A2 Novel copolymer and photosensitive material containing the same Daikin Kogyo Co., Ltd. (JP) 1983-12-28 EP claimed
EP-0040841-A1 Photosensitive material Daikin Kogyo Co., Ltd. (JP) 1981-12-02 EP claimed
CN-102089262-A Derivatives of 3- (2-hydroxy-5-methylphenyl) -N, N-diisopropyl-3-amphetamine and methods of use thereof CONCERT PHARMACEUTICALS INC 2011-06-08 CN disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed
EP-0096845-B1 NOVEL COPOLYMER AND PHOTOSENSITIVE MATERIAL CONTAINING THE SAME Daikin Kogyo Co., Ltd. (JP) 1986-09-10 EP disclosed
US-4529783-A Fluorine containing acrylic monomer DAIKIN KOGYO COMPANY, LTD. (JP) 1985-07-16 US disclosed
EP-0040841-B1 PHOTOSENSITIVE MATERIAL Daikin Kogyo Co., Ltd. (JP) 1985-03-13 EP disclosed
US-4433152-A ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT NIPPON CHEMIPHAR CO., LTD. (JP) 1984-02-21 US disclosed
US-4424325-A COPOLYMER OF PERFLUOROALKYL OR PERFLUOROALKENYL ACRYLIC MONOMER DAIKIN KOGYO CO., LTD. (JP) 1984-01-03 US disclosed
EP-0096845-A2 Novel copolymer and photosensitive material containing the same Daikin Kogyo Co., Ltd. (JP) 1983-12-28 EP disclosed
EP-0040841-A1 Photosensitive material Daikin Kogyo Co., Ltd. (JP) 1981-12-02 EP disclosed