Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | FABP3 | P05413 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | F7 | P08709 | 4/20 | 0.51 |
| ▸ | F3 | P13726 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239576 | 1.00 | ALDH1A1 (0.55) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL3317697 | 0.93 | ALDH1A1 (0.67) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4236798 | 0.93 | ALDH1A1 (0.67) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL3317694 | 0.93 | ALDH1A1 (0.67) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6294264 | 0.91 | ALDH1A1 (0.63) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6292848 | 0.89 | TRPV1 (0.58) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6292850 | 0.89 | TRPV1 (0.58) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL7036873 | 0.89 | ALDH1A1 (0.61) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4241268 | 0.84 | ALDH1A1 (0.44) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4239573 | 0.81 | FABP3 (0.54) | ALDH1A1FABP3TRPV1PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149496-A1 | TREATMENT OF DIABETES AND COMPLICATIONS THEREOF AND RELATED DISORDERS | CENTRAL NORTHERN ADELAIDE HEALTH SERVICE (AU) | 2009-12-17 | — | — | WO | disclosed |
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218000-A4 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218000-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021172-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |