Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | FABP3 | P05413 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | F7 | P08709 | 4/20 | 0.51 |
| ▸ | F3 | P13726 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236798 | 1.00 | ALDH1A1 (0.67) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL3317694 | 1.00 | ALDH1A1 (0.67) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6294264 | 0.98 | ALDH1A1 (0.63) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL7036873 | 0.96 | ALDH1A1 (0.61) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6292848 | 0.93 | TRPV1 (0.58) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL6292850 | 0.93 | TRPV1 (0.58) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4282518 | 0.93 | ALDH1A1 (0.55) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4239576 | 0.93 | ALDH1A1 (0.55) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL4239573 | 0.89 | FABP3 (0.54) | ALDH1A1FABP3TRPV1PPARGKDM4E | |
| SCHEMBL3319829 | 0.89 | FABP3 (0.54) | ALDH1A1FABP3TRPV1PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104546-A1 | MODULATORS OF ANTIGEN-DEPENDENT T CELL PROLIFERATION | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE (AU) | 2010-04-29 | — | — | US | disclosed |
| EP-2120916-A1 | MODULATORS OF ANTIGEN-DEPENDENT T CELL PROLIFERATION | Children, Youth and Womens's Health Service Incorporated (AU) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009006668-A1 | MODULATORS OF ANTIGEN-DEPENDENT T CELL PROLIFERATION | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE (AU) | 2009-01-15 | — | — | WO | disclosed |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2004-12-16 | — | — | US | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 282/4885FABP3 738/4885TRPV1 2887/4885 |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 305/4885FABP3 780/4885TRPV1 3120/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885FABP3 289/4885TRPV1 1291/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | ALDH1A1 316/4885FABP3 834/4885TRPV1 3232/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885FABP3 289/4885TRPV1 1291/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | ALDH1A1 856/4885FABP3 396/4885TRPV1 1292/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | ALDH1A1 884/4885FABP3 289/4885TRPV1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.