Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585099 | 0.87 | SLC6A9 (0.71) | SLC6A9POLBGAAPKM | |
| SCHEMBL5584840 | 0.86 | SLC6A9 (0.68) | SLC6A9USP2 | |
| SCHEMBL5584895 | 0.84 | SLC6A9 (0.66) | SLC6A9POLBUSP2 | |
| SCHEMBL5585003 | 0.84 | SLC6A9 (0.66) | SLC6A9POLBUSP2 | |
| SCHEMBL5584923 | 0.84 | SLC6A9 (0.66) | SLC6A9USP2 | |
| SCHEMBL5584555 | 0.84 | SLC6A9 (0.66) | SLC6A9POLBUSP2 | |
| SCHEMBL5584496 | 0.83 | SLC6A9 (0.78) | SLC6A9 | |
| SCHEMBL14538122 | 0.83 | SLC6A9 (0.78) | SLC6A9 | |
| SCHEMBL5584931 | 0.83 | SLC6A9 (0.72) | SLC6A9USP2 | |
| SCHEMBL5591035 | 0.83 | SLC6A9 (1.00) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684759-A4 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | MERCK & CO INC (US) | 2009-06-10 | — | — | EP | disclosed |
| EP-1684759-A2 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | Merck & Co., Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005046601-A2 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2005-05-26 | — | — | WO | disclosed |