Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584840 | 0.91 | SLC6A9 (0.68) | SLC6A9USP2KDM4EGLAP2RX7 | |
| SCHEMBL761952 | 0.85 | SLC6A9 (0.68) | SLC6A9USP2KDM4EGLA | |
| SCHEMBL8247219 | 0.85 | SLC6A9 (0.68) | SLC6A9USP2KDM4EGLA | |
| SCHEMBL5584931 | 0.85 | SLC6A9 (0.72) | SLC6A9USP2 | |
| SCHEMBL4282569 | 0.84 | SLC6A9 (0.71) | SLC6A9USP2 | |
| SCHEMBL5585136 | 0.84 | SLC6A9 (0.81) | SLC6A9P2RX7 | |
| SCHEMBL5585099 | 0.83 | SLC6A9 (0.71) | SLC6A9 | |
| SCHEMBL5585003 | 0.82 | SLC6A9 (0.66) | SLC6A9USP2 | |
| SCHEMBL5584555 | 0.82 | SLC6A9 (0.66) | SLC6A9USP2 | |
| SCHEMBL5584895 | 0.82 | SLC6A9 (0.66) | SLC6A9USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | SLC1A2, SLC1A1, SLC1A3 | SLC6A9 10/4885USP2 2886/4885KDM4E 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.