Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180252 | 0.87 | ALDH1A1 (0.50) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 | |
| SCHEMBL31325535 | 0.85 | ALDH1A1 (0.48) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 | |
| Bromide SCHEMBL20424457 | 0.85 | ALDH1A1 (0.48) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 | |
| SCHEMBL15094975 | 0.81 | ALDH1A1 (0.43) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 | |
| Benzoyl Formic Acid SCHEMBL31113376 | 0.80 | CES2 (0.51) | SMN1; SMN2LMNAKMT2AABCG2CYP1A2 | |
| Acetic Acid SCHEMBL6271569 | 0.78 | CYP3A4 (0.52) | CYP3A4USP2MAPK1SMN1; SMN2LMNA | |
| SCHEMBL31747503 | 0.75 | CA12 (0.37) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 | |
| SCHEMBL10702455 | 0.74 | CA4 (0.43) | CYP3A4SMN1; SMN2LMNAKMT2AABCG2 | |
| Propylamine SCHEMBL12465622 | 0.74 | CYP1A2 (0.47) | CYP3A4CYP1A2ALDH1A1CA12CA1 | |
| SCHEMBL31747558 | 0.73 | CA12 (0.35) | CYP3A4USP2MAPK1SMN1; SMN2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190025324-A1 | PEPTIDE SEQUENCING DIRECTLY FROM SOLID SURFACES | NATIONAL SCIENCE FOUNDATION | 2019-01-24 | — | — | US | claimed |
| US-20090142851-A1 | METHOD FOR SELECTIVELY RECOVERING C-TERMINAL PEPTIDE OF PROTEIN AND METHOD FOR DETERMINING AMINO ACID SEQUENCE OF C-TERMINAL PEPTIDE OF PROTEIN USING THE SAME | SHIMADZU CORPORATION (JP) | 2009-06-04 | — | — | US | claimed |
| WO-2025229843-A1 | PEPTIDE PURIFICATION METHOD AND PEPTIDE PURIFICATION KIT | 株式会社島津製作所 | 2025-11-06 | — | — | WO | disclosed |
| US-20190025324-A1 | PEPTIDE SEQUENCING DIRECTLY FROM SOLID SURFACES | NATIONAL SCIENCE FOUNDATION | 2019-01-24 | — | — | US | disclosed |
| US-20090142851-A1 | METHOD FOR SELECTIVELY RECOVERING C-TERMINAL PEPTIDE OF PROTEIN AND METHOD FOR DETERMINING AMINO ACID SEQUENCE OF C-TERMINAL PEPTIDE OF PROTEIN USING THE SAME | SHIMADZU CORPORATION (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090042741-A1 | MICROARRAY OF THREE-DIMENSIONAL HETEROPOLYMER MICROSTRUCTURES AND METHOD THEREFOR | ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090142851-A1 | METHOD FOR SELECTIVELY RECOVERING C-TERMINAL PEPTIDE OF PROTEIN AND METHOD FOR DETERMINING AMINO ACID SEQUENCE OF C-TERMINAL PEPTIDE OF PROTEIN USING THE SAME | ANPEP, RNPEP, PTMS | CYP3A4 4677/4885USP2 601/4885MAPK1 3981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.