Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL28112516 | 0.84 | TTR (0.55) | TSHRALDH1A1TTRMEN1KMT2A | |
| Dioxane SCHEMBL440246 | 0.79 | — | — | |
| 1,2-Dichloroethane SCHEMBL27852850 | 0.79 | — | — | |
| Dioxane SCHEMBL23167502 | 0.79 | TTR (0.60) | TSHRALDH1A1TTRMEN1KMT2A | |
| Dioxane SCHEMBL27544988 | 0.78 | TSHR (0.63) | TSHRALDH1A1TDP1TTRMEN1 | |
| Morpholine SCHEMBL16600031 | 0.78 | MEN1 (0.58) | TSHRALDH1A1TDP1MEN1KMT2A | |
| Oxirane SCHEMBL29157258 | 0.76 | — | — | |
| Dioxane SCHEMBL15422680 | 0.75 | TTR (0.55) | TSHRALDH1A1TTRMEN1KMT2A | |
| Oxirane SCHEMBL20224024 | 0.74 | — | — | |
| SCHEMBL29249 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156507-A1 | Cell permeable conjugates of peptides for inhibition of protein kinases | CUREGENICS LTD. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156507-A1 | Cell permeable conjugates of peptides for inhibition of protein kinases | MAP3K20, MAP3K19, MAP4K2 | TSHR 2160/4885ALDH1A1 4613/4885TDP1 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.