Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL27631597 | 0.85 | — | — | |
| Morpholine SCHEMBL27498050 | 0.84 | TSHR (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL7243887 | 0.82 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL11540752 | 0.82 | TSHR (0.54) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL5414836 | 0.82 | TSHR (0.54) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL8106569 | 0.82 | TSHR (0.54) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL8005743 | 0.81 | MEN1 (0.55) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL2744013 | 0.80 | — | — | |
| Dioxane SCHEMBL4282590 | 0.78 | TSHR (0.54) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| Morpholine SCHEMBL7996463 | 0.78 | MEN1 (0.92) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015043492-A1 | SUBSTITUTED UREA DERIVATIVES AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |